New AI-based tests tell consumers their biological age by determining the rate at which organs, cells and tissues are deteriorating.
Startups are launching at-home tests that collect blood, urine or cheek swabs to analyze changes in the epigenome, the mechanism that helps read the DNA code.
Here, Tally Health, one such company, recently presented a 13-year study showing that epigenetic changes can be safely reversed in mice to improve tissue function, such as repairing cellular programs.
The company believes that the same can be done with people.
Elysium contains a biological age test that provides “science-backed recommendations” to help consumers improve bodily functions in the hope of turning back the clock.
Consumer interest in longevity has grown, with the global longevity economy expected to reach $27 trillion in 2026 and the longevity technology sector to reach $2.7 trillion by 2025.
While the idea of ”turning back time” sounds like science fiction, the concept is a real service that can be purchased for $299 a month.
The current biological tests, using the power of the epigenetic clock, are a predictive test based on data from 8,000 biological samples from 51 healthy human tissues and cell types.
It was developed by Stephen Horvath, a geneticist and biostatistician at the University of California, Los Angeles, in 2013 and measures DNA methylation patterns associated with aging and disease, and uses an algorithm to determine a person’s age, reports WIRED.
Tally Health launched its technology on February 23rd, promoting it to improve health and lifespan at the cellular level.
“DNA is no longer the only predictor of our fate or lifespan,” Harvard co-founder and biologist Dr. David Sinclair said in a statement. “Less than 10% of our lifespan is determined by our genes; the result of our daily lifestyle choices and our environment.” Many studies and interventions in the near future will be focused on increasing human lifespan.The interest in aging has generated huge research ideas in this area around the world and has pushed gerontology to a new level.”
Tally Health requires a simple cheek swab analyzed by the TallyAge watch, which has been trained on the largest adult cheek tissue DNA dataset of more than 8,000 samples.
After analyzing a user sample, they receive personalized insights and recommendations to help extend life, as well as unique supplements to help along the way.
“We created Tally to be a science-based health care assistant for anyone who wants to improve their health and increase life expectancy,” said Melanie Goldie, CEO of Tally.
The service is offered on a monthly subscription, allowing members to test frequently.
Consumers can choose between three, six or 12 months and pay between $199 and $129 per month.
Elysium was also co-founded by its chief scientist, Dr. Leonard Guarente, who began researching aging in 1982 and uses the epigenetic clock as the basis of the company’s technology.
Guarente, who is also an MIT professor, said the epigenetic clock is a big advance in the field of aging because it allows biological aging to be accurately studied without the need for a long-term timeline.
For consumers, the indicator was the first and most accurate indicator of aging and remains the only product to offer a simple saliva-based biological age test.
The addition of nine systems expands this concept of measuring aging in specific ways that provide more useful information for lifestyle changes to improve health. The use of this new technology within the Center for Research on Aging provides an excellent opportunity to significantly accelerate breakthroughs in the field of aging through direct collaboration with consumers who choose to subscribe and get the greatest potential benefit.
The Elysium test is called Index and requires a sample of consumers, which is then fed into machine learning algorithms that measure 10 different aspects of aging.
According to Elysium, “Using the superior accuracy of our epigenetic screening algorithms (APEX) platform, Elysium calculates your biological and systemic age by examining the regions of your DNA where methylation has occurred.”
DNA methylation is defined as a genetic modification that affects how genes are expressed, and the genome-wide pattern predictably changes with age.
Source: Dell Inclines.