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Unveiling the Optimal Biomarker for Liver Cancer Detection

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Warren Henry
Warren Henry is a tech geek and video game enthusiast whose engaging and immersive narratives explore the intersection of technology and gaming.

Scientists at the Medical University of South Carolina have discovered the best biomarker for diagnosing liver cancer, allowing for rapid and early diagnosis.

Cancer Research Communications notes that intrahepatic cholangiocarcinoma is a malignant tumor and the second most common type of liver cancer. This type of cancer is considered very aggressive, and if detected late, the statistical five-year survival rate does not exceed 8 percent. While early diagnosis can cure 50 percent of patients.

Until now, it was believed that diagnosing this type of cancer at an early stage is difficult. Because its symptoms are similar to those of other liver diseases. In addition, biomarkers for intrahepatic cholangiocarcinoma are not specific for this disease. But now researchers have discovered a unique molecule in tissue and blood samples from patients that only appears when they have this type of cancer. These changes are characteristic of N-glycan, a type of sugar found in proteins. The discovered biomarker will help diagnose liver cancer only by a blood test, without the need for a biopsy analysis.

The researchers did not determine the cause of the N-glycan change, so they decided to continue studying these sugars and identify the proteins associated with these changes and why.

Source: Linta. EN

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